Thomas F. Wilson

Ed Klingbottom

Karim Prince

Roy Dubro

M. Emmet Walsh

Stanley

Brion James

Air Force

Wigald Boning

Dr. Strangemeister

Ben Stein

Men in Strangemeister's Head

George Kennedy

Army

Donna D'Errico

Press Secretary

Barry Bostwick

President Smith

Rodger Halston

Glaxxon

Don Stroud

Old Bob

John Bishop

G-Man

Patricia Elliott

Girl Scout Leader

Melissa Rivers

Female Reporter #1

Dave Fennoy

Glaxxon (voice)

Dee Bradley Baker

Subordinate Alien (voice)

Jennifer Coolidge

Charles Philip Moore

Alien #1

Amy Kidd

Female Reporter #2

Blaine Etcheverry

Male Reporter

Lacey Taylor Robbins

Girl Scout

Michael McDonald

Secret Service Agent

Manny Fernandez

Paul Di Franco

General Pandemonium

Carlos Bernard

Alien

Rob Kerchner

Lifeguard

Preston Ahearn

Danny Mann

Alien #1 (voice)

Susan Silo

Alien #2 (voice)

Bobby Edner

Michael Reardon

Spock

Mary Ann Schmidt

Bikini Girl

Seth Bailey

John Wayne Gacy's 'Pogo the Clown' (uncredited)

Rob Paulsen

Dr. Strangemeister (voice) (uncredited)