Song and Dance Man was based on the play of the same name by George M. Cohan. Tom Moore plays vaudevillian Happy Farrell, who gives up show biz to take a "civilian" job. Finding success in the business world, Happy tries to go back on stage, only to find that it isn't quite so easy the second time around. Meanwhile, our hero's former vaude partner Leola Lane (Bessie Love), now a headliner at the Palace, gives it all up to become the bride of artist Joseph Murdock