This documentary depicts the filmmaker Alejandro Jodorowsky talking about his life, his loves, his career as a filmmaker, graphic novelist, and workshop leader, and his eccentricities including tarot reader and theatrical director during The Panic Movement. Directed by Louis Mouchet, La Constellation Jodorowsky includes a lengthy on-camera interview with Jodorowsky in Spanish with subtitles. Marcel Marceau, Fernando Arrabal, Peter Gabriel, Jean "Moebius" Giraud, and Jean Pierre Vignau make appearances discussing their various projects with the director. In addition to the interview and film clips, Mouchet features some bizarre footage from Jodorowsky’s absurdist plays in which topless women splattered with paint writhe around the stage in a theatrical production meant to represent The Panic Movement, i.e., an artistic expression in which reason cannot fully express the human experience.