Annie (Ann Gillis), an orphan, (based on Harold Gray's comic strip but who is at no point in the film called 'Little Orphan Annie), is befriended by a fight manager, 'Pop' Corrigan (J. Farrell MacDonald). She brings him Johnny Adams (Robert Kent), a promising prizefighter. Annie gets the people of the neighborhood to finance his training. But on the night of Johnny's big fight, a gambling syndicate locks him in a gymnasium and it appears the neighborhood folks will lose their investment.