The premise of Aik Sitam Aur is revolving around the life struggle and tragedies of Zainab, her daughter Ushna and the spiteful behavior of her brothers Rafaqat, Shujaat, and their wives. Zainab’s life became a roller coaster ride filled with ups and downs as she struggles to make her ends meet and find a refuge for her daughter and herself. On the other hand Naeema, the paralyzed wife of Wahab wants her husband to remarry so their family can be better-taken care of.