Each episode toggles between the renowned surgeons of Manhattan's New York Presbyterian Hospital and the gritty world of trauma surgeons at Newark's University Hospital where the ER is a doorway to the mean streets of one of America's most violent cities. Sometimes poignant and often uproarious, this limited series takes a deep dive into high stakes medicine through the eyes of unforgettable characters, including a hilarious trio of returning ER nurses who must cope with tricky personal crises while caring for some of the nation's most bossy patients. Mehmet Oz rounds out the character roster with his extraordinary surgical skills on full display as his deft hands work to fix damaged hearts and save lives.